“A TEST THAT CAN TAILOR YOUR THERAPY”
The United States suffers from the severe health issue of adverse drug events (ADEs), which affect those taking medication of any level, dosage, or quantity. To fight the human health factors and financial weight of ADEs, MicroGen Health uses modern pharmacogenomics genomic testing. This panel presents our clients with clues to how their bodies may respond to different therapeutic drugs. This is done by examining the influence of various genetic factors concerning absorption, distribution, metabolism, elimination, and action of therapeutic drug treatment.
We offer our precise panel results to clients and their medical providers as guidelines for future recommendations of appropriate drugs and dosages. This, in turn, increases therapeutic efficacy while minimizing possible future ADEs. Recent genetic research has shown that a significant portion of the patient population is dosing ineffectively due, at least in part, to a genetic mismatch between the metabolism and medication.
This test will help inform clients of their genetic makeup, which, coupled with modifications to their lifestyle and nutrition, may modify their drug usage. This information leads to not only higher-quality lives but to the actual prevention of life-threatening drug missteps. The USFDA has made this panel mandatory for certain drugs to ensure safety and efficacy. When everything in life can be customized, why not customize your therapy?
Pharmacogenomic panel covers 30 genetic markers
This is an 9-gene panel customized to cardiovascular medications such as anti-coagulants, anti-platelet agents and statins. The genes covered are:
This is a 14-gene panel customized for anti-psychotic and anti-depressant medications. Genes covered are:
This is an 3-gene panel customized for opioids and non-opioids. The genes covered are:
This is a 4-gene panel customized for anti-cancer agents. The genes covered are:
This is a 30-gene panel for comprehensive pharmacogenetic testing. The genes covered are:
ABCG2, ADRA2A, ANKK1, ApoE, BDNF, CACNA1C, COMT, CYP1A2, CYP2B6, CYP2C19, CYP2C9, CYP4F2, CYP2D6, CYP3A4, CYP3A5, DBH, F2, F5, MTHFR, GRIK4, HTR2A, HTR2C, OPRK1, OPRM1, SLCO1B1, TPMT, VKORC1, UGT2B15, ABCB1, SLC6A3/DAT1.
The earlier clients can be tested, the better. If a client is concerned about the possibility of a future diagnosis, they should reach out to their primary care provider for guidance. That provider will most likely review certain personal history and background medical information to determine if testing would be appropriate. Some of the reasons for ordering this test include:
Primary physicians should first conduct a pre-test genetic counseling session with their patients before referring them for testing. This is so all the appropriate questions are answered about the potential benefits and limitations of the test. There will then be a trained laboratory technician that will collect a whole blood sample or buccal swab of the client into a specific testing container. That sample will then be sent to our labs in a safe, temperature-controlled setting.s
Genomic DNA will be carefully extracted from the collected sample by our expert technicians using the latest technology. Our lab will then assess the quality and quantity of the sample for genetic markers using Next Generation Sequence. The genetic markers will be evaluated using Taqman OpenArray PGX Express panel on a real-time PCR machine, “QuantStudioTM12K Flex”. The genetic data will be processed further using Bioinformatics tools to understand its impact on the drug metabolizer phenotype.
All test reports will be shared with the concerned physician or medical professional, who will guide the client on the suitability of specific medications and their respective dosage schedules.
At MicroGen Health, we strive to provide only evidence-backed test results using experienced technicians and experts with the latest technology. We protect our client’s privacy according to industry standards and seek to have a professional customer interaction each and every time. If you would like to begin your test or have any other questions, please reach out to our team using our contact page. Thank you for considering MicroGen Health for your health care diagnostics.
|Warfarin||CYP2C9, VKORC1, CYP4F2|